COMBINED ANTIFUGAL ACTIVITIES OF ALOE VERA, LIME, AND GARLIC EXTRACTS AGAINST CANDIDA ALBICANS AND MALASSEZIA FURFUR

Abstract

This study, combined antifugal activities of Aloe vera, Lime and Garlic extracts, against candida albicans and Malassezia furfur was carried out Candida albicans and. Malassezia furfur are opportunistic pathogens causing various fungal infections, Natural products offer promising alternatives to synthetic antifungals, The aim of this study is to determine the combined antibacterial activity of Aloe vera, Lime, and Garlic extracts against selected pathogenic fungi, (Candida albicans, M, furfur). Antifungal activiities were determined by Agar well diffusion and broth microdilution assays, Combination. of Aloe vera, Lime, and Garlic extracts showed synergistic antifungal effects, with zones of inhibition, (32-35 mm) and reduced MICs (6.25-12.5 μg/mL) against both pathogens, this study demonstrates the enhanced antifungal efficacy of Aloe vera, Lime, and Garlic extracts combination, offering a natural and effective treatment strategy for fungal infections caused by Candida albicans and. Malassezia furfur. Antifugal activities of the mixtures were determined by Agar well disc diffusion technique, and brother micro dilution factor assays, the antifugal activities of each of plant extract againsts was determine separately. before the conbined antifugal activities, the results showed zones inhibition ranging from 18.00- 35.00mmfor the in individual plant extract, the combined antifugal activities of the mixture showed zoness of inhibitionDeviation